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Substrates for peptidase N09.001: intein-containing V-type proton ATPase catalytic subunit A

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
V-type proton ATPase catalytic subunit A P17255 2-1071 peptide-Gly283+Cys-peptide P NT Ile Tyr Val Gly Cys Phe Ala Lys Mizutani et al., 2002
V-type proton ATPase catalytic subunit A P17255 2-1071 peptide-Asn737+Cys-peptide P NT Val Val His Asn Cys Gly Glu Arg Mizutani et al., 2002
V-type proton ATPase catalytic subunit A P38078 1-1088 peptide-Gly283+Cys-peptide P NT Ile Tyr Val Gly Cys Phe Thr Lys Gu et al., 1993
V-type proton ATPase catalytic subunit A P38078 1-1088 peptide-Asn754+Cys-peptide P NT Leu Val His Asn Cys Gly Glu Arg Gu et al., 1993
vacuolar ATPase Q2P9R3 1-395 peptide-Asn394+Cys N CS Val Val His Asn Cys - - -
vacuolar membrane ATPase subunit a Q874F9 1-1046 peptide-Gly269+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane ATPase subunit a Q874F9 1-1046 peptide-Asn723+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg
vacuolar membrane ATPase subunit a Q874G1 1-960 peptide-Gly245+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Glu Lys
vacuolar membrane ATPase subunit a Q874G1 1-960 peptide-Asn659+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane ATPase subunit a Q874G4 1-1098 peptide-Gly271+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane ATPase subunit a Q874G4 1-1098 peptide-Asn772+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane ATPase subunit a Q874G5 1-1101 peptide-Gly265+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane ATPase subunit a Q874G5 1-1101 peptide-Asn782+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane ATPase subunit a Q874G6 1-978 peptide-Gly276+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ser Lys
vacuolar membrane ATPase subunit a Q874G6 1-978 peptide-Asn686+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane ATPase subunit a Q874G7 1-992 peptide-Gly276+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane ATPase subunit a Q874G7 1-992 peptide-Asn691+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane ATPase subunit a 1 Q874G3 1-1067 peptide-Gly267+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane ATPase subunit a 1 Q874G3 1-1067 peptide-Asn766+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane ATPase subunit a 2 Q874G2 1-1070 peptide-Gly267+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane ATPase subunit a 2 Q874G2 1-1070 peptide-Asn769+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0G2 1-541 peptide-Gly18+Cys-peptide N CS Val Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0G2 1-541 peptide-Asn468+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0G3 1-533 peptide-Gly10+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0G3 1-533 peptide-Asn460+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0G4 1-547 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0G4 1-547 peptide-Asn474+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0G6 1-547 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0G6 1-547 peptide-Asn474+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0G7 1-505 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Glu Lys
vacuolar membrane H-ATPase Q8J0G7 1-505 peptide-Asn432+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0G8 1-593 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0G8 1-593 peptide-Asn520+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0G9 1-592 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0G9 1-592 peptide-Asn519+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0H0 1-608 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0H0 1-608 peptide-Asn535+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0H1 1-545 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0H1 1-545 peptide-Asn472+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0H2 1-519 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vacuolar membrane H-ATPase Q8J0H2 1-519 peptide-Asn451+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg
vacuolar membrane H-ATPase Q8J0H3 1-501 peptide-Gly18+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ser Lys
vacuolar membrane H-ATPase Q8J0H3 1-501 peptide-Asn428+Cys-peptide N CS Leu Val His Asn Cys Gly Glu Arg
vMA1 Q96UY3 1-516 peptide-Gly28+Cys-peptide N CS Ile Tyr Val Gly Cys Phe Ala Lys
vMA1 Q96UY3 1-516 peptide-Asn482+Cys-peptide N CS Val Val His Asn Cys Gly Glu Arg

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