Substrates for peptidase N08.001: poliovirus capsid VP0-type self-cleaving protein

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
genome polyprotein P03300 2-341 peptide-Asn69+Ser-peptide P NT Pro Met Leu Asn Ser Pro Asn Ile Hogle et al., 1985
genome polyprotein P06209 1-2206 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Val
genome polyprotein Q66474 1-2191 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
genome polyprotein P03302 1-2206 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Val
genome polyprotein P23069 1-2205 peptide-Asn69+Ser-peptide P CS Pro Thr Leu Asn Ser Pro Asn Ile
genome polyprotein P36290 1-2214 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Val
genome polyprotein P21404 1-2201 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
genome polyprotein P03300 1-2209 peptide-Asn69+Ser-peptide P CS Pro Met Leu Asn Ser Pro Asn Ile
genome polyprotein P22055 1-2206 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Val
genome polyprotein Q9QL88 1-2184 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
genome polyprotein Q9WN78 1-2194 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
genome polyprotein P08292 1-2183 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
genome polyprotein P29813 1-2195 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
genome polyprotein Q9YLJ1 1-2196 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
genome polyprotein O91734 1-2184 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
polyprotein Q7T7N7 1-2206 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein C6EN10 1-2213 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein C7B297 1-2219 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein C6EN04 1-2212 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein C6ZF04 1-2192 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein Q6W9G2 1-2196 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
polyprotein B0YIF4 1-2194 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
polyprotein A1Z2X3 1-2187 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
polyprotein C6EN31 1-2207 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Val
polyprotein Q6W9F2 1-2194 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
polyprotein Q401S2 1-2214 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein Q7T7P1 1-2213 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein Q401S3 1-2206 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Val
polyprotein Q6W9G0 1-2196 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
polyprotein B6DVM0 1-2182 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
polyprotein A3FEX0 1-2186 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
polyprotein Q5UEA2 1-2185 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Val
polyprotein Q7T7P2 1-2212 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein Q6W9F4 1-2193 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
polyprotein Q6W9F6 1-2196 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Lys Ala
polyprotein Q8V613 1-2183 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Val
polyprotein Q05ED4 1-2200 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Thr Ala
polyprotein Q7T7N9 1-2207 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Asn Ile
polyprotein B0YIF3 1-2196 peptide-Asn69+Ser-peptide P CS Pro Ala Leu Asn Ser Pro Ser Ala
polyprotein B9V471 1-2166 peptide-Gln69+Ser-peptide P CS Pro Thr Leu Gln Ser Pro Ser Val