Substrates for peptidase M9G.028: magaininase

Summary Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
CPF Gly-Phe-Ala-Ser-Phe-Leu-Gly-Lys-Ala-Leu+Lys-Ala-Ala-Leu-Lys-Ile-Gly-Ala-Asn-Leu-Leu-Gly-Gly-Thr-Pro-Gln-Gln P Gly Lys Ala Leu Lys Ala Ala Leu Resnick et al., 1991
magainin 2 P11006 129-151 Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys+Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser P His Ser Ala Lys Lys Phe Gly Lys Resnick et al., 1991
PGLa antimicrobial peptide Q99134 39-59 Gly-Met-Ala-Ser-Lys-Ala-Gly-Ala-Ile-Ala-Gly+Lys-Ile-Ala-Lys-Val-Ala-Leu-Lys-Ala-Leu P Ala Ile Ala Gly Lys Ile Ala Lys Resnick et al., 1991
xenopsin precursor P07198 39-81 Gln-Trp-Ala-Ser-Lys-Ile-Gly-Gln-Thr-Leu-Gly+Lys-Ile-Ala-Lys-Val-Gly-Leu-Lys-Glu-Leu-Ile-Gln-Pro-Lys P Gln Thr Leu Gly Lys Ile Ala Lys Resnick et al., 1991