Substrates for family M87 unassigned peptidases

Summary Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
ca(2+)-activated chloride channel Q75ZI5 1-903 peptide-Lys700+Ser-peptide P NT Gln Lys Asn Lys Ser Leu Tyr Ile Yurtsever et al., 2012
calcium-activated chloride channel Q05KA7 1-905 peptide-Lys703+Ala-peptide P NT Gln Lys Asn Lys Ala Leu Tyr Ile Yurtsever et al., 2012
uncharacterized protein F1N4Y8 1-905 peptide-Lys702+Val-peptide P NT Pro Gln Asn Lys Val Leu Tyr Val Yurtsever et al., 2012
uncharacterized protein F7CAB1 1-904 peptide-Lys701+Ala-peptide P NT Gln Gln Asn Lys Ala Leu Tyr Ile Yurtsever et al., 2012