Substrates for peptidase M64.001: IgA peptidase (Clostridium ramosum-type)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
immunoglobulin IgA1 P01876 1-353 peptide-Pro221+Val-peptide N Val Pro Cys Pro Val Pro Ser Thr Fujiyama et al., 1986 17177
immunoglobulin IgA2:A2m(1) P01877 1-340 peptide-Pro221+Val-peptide N Val Pro Cys Pro Val Pro Pro Pro Fujiyama et al., 1986 17178