Substrates for peptidase M50.001: site 2 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
cAMP responsive element binding protein 3-like 3	Q91XE9	1-479	peptide-Leu359+His-peptide	P	Ser	Arg	Thr	Leu	His	Asn	His	Ala	Zhang et al., 2006	18334
sterol regulatory element binding protein-2	Q12772	1-1141	peptide-Leu484+Cys-peptide	P	Arg	Ile	Leu	Leu	Cys	Val	Leu	Thr	Duncan et al., 1998	17873
sterol regulatory element binding protein-2	Q12772	1-1141	peptide-Leu490+Cys-peptide	P	Leu	Thr	Phe	Leu	Cys	Leu	Ser	Phe		17171