Substrates for peptidase M28.021: AaaA aminopeptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Arg-Ala	Arg+Ala	N	-	-	-	Arg	Ala	-	-	-	Luckett et al., 2012
Arg-Asp	Arg+Asp	N	-	-	-	Arg	Asp	-	-	-	Luckett et al., 2012
Arg-Gln	Arg+Gln	N	-	-	-	Arg	Gln	-	-	-	Luckett et al., 2012
Arg-Glu	Arg+Glu	N	-	-	-	Arg	Glu	-	-	-	Luckett et al., 2012
Arg-Ile	Arg+Ile	N	-	-	-	Arg	Ile	-	-	-	Luckett et al., 2012
Arg-Leu	Arg+Leu	N	-	-	-	Arg	Leu	-	-	-	Luckett et al., 2012
Arg-Met	Arg+Met	N	-	-	-	Arg	Met	-	-	-	Luckett et al., 2012
Arg-NHPhNO2	Arg+NHPhNO2	S	-	-	-	Arg	NAN	-	-	-	Luckett et al., 2012
Arg-Phe	Arg+Phe	N	-	-	-	Arg	Phe	-	-	-	Luckett et al., 2012
Arg-Ser	Arg+Ser	N	-	-	-	Arg	Ser	-	-	-	Luckett et al., 2012
Arg-Trp	Arg+Trp	N	-	-	-	Arg	Trp	-	-	-	Luckett et al., 2012
Arg-Tyr	Arg+Tyr	N	-	-	-	Arg	Tyr	-	-	-	Luckett et al., 2012
Arg-Val	Arg+Val	N	-	-	-	Arg	Val	-	-	-	Luckett et al., 2012