Substrates for peptidase M28.020: AM-1 aminopeptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-NHPhNO2 Ala+NHPhNO2 S - - - Ala NAN - - - Murai et al., 2004
Leu-NHPhNO2 Leu+NHPhNO2 S - - - Leu NAN - - - Murai et al., 2004
Lys-NHPhNO2 Lys+NHPhNO2 S - - - Lys NAN - - - Murai et al., 2004
Pro-NHPhNO2 Pro+NHPhNO2 S - - - Pro NAN - - - Murai et al., 2004
Val-NHPhNO2 Val+NHPhNO2 S - - - Val NAN - - - Murai et al., 2004