Substrates for peptidase M28.004: aminopeptidase AC

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Ala-Phe	Ala+Phe	N	-	-	-	Ala	Phe	-	-	-	Zhang et al., 2001
Leu-NHPhNO2	Leu+NHPhNO2	S	-	-	-	Leu	NAN	-	-	-	Zhang et al., 2001
Leu-Phe	Leu+Phe	N	-	-	-	Leu	Phe	-	-	-	Zhang et al., 2001
Met-NHPhNO2	Met+NHPhNO2	S	-	-	-	Met	NAN	-	-	-	Zhang et al., 2001
Met-Phe	Met+Phe	N	-	-	-	Met	Phe	-	-	-	Zhang et al., 2001
Phe-Ala	Phe+Ala	N	-	-	-	Phe	Ala	-	-	-	Zhang et al., 2001
Phe-Gly	Phe+Gly	N	-	-	-	Phe	Gly	-	-	-	Zhang et al., 2001
Phe-Gly-Gly	Phe+Gly-Gly	N	-	-	-	Phe	Gly	Gly	-	-	Zhang et al., 2001
Phe-Leu	Phe+Leu	N	-	-	-	Phe	Leu	-	-	-	Zhang et al., 2001
Phe-Met	Phe+Met	N	-	-	-	Phe	Met	-	-	-	Zhang et al., 2001
Phe-Phe	Phe+Phe	N	-	-	-	Phe	Phe	-	-	-	Zhang et al., 2001
Phe-Phe-Pro-Glu-Ala	Phe+Phe-Pro-Glu-Ala	N	-	-	-	Phe	Phe	Pro	Glu	Ala	Zhang et al., 2001
Val-NHPhNO2	Val+NHPhNO2	S	-	-	-	Val	NAN	-	-	-	Zhang et al., 2001