Substrates for peptidase M28.001: aminopeptidase Y

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-NHMec Ala+NHMec S - - - Ala AMC - - - Nakai & Yasuhara, 2004
Ala-NHMec Ala+NHMec S - - - Ala AMC - - - Monod et al., 2005
Ala-NHMec Ala+NHMec S - - - Ala AMC - - - Monod et al., 2005
Arg-Arg-NHMec Arg+Arg-NHMec S - - - Arg Arg AMC - - Nakai & Yasuhara, 2004
Arg-NHMec Arg+NHMec S - - - Arg AMC - - - Nakai & Yasuhara, 2004
Asn-NHMec Asn+NHMec S - - - Asn AMC - - - Monod et al., 2005
Asn-NHMec Asn+NHMec S - - - Asn AMC - - - Monod et al., 2005
Cys-NHMec Cys+NHMec S - - - Cys AMC - - - Monod et al., 2005
Gln-NHMec Gln+NHMec S - - - Gln AMC - - - Monod et al., 2005
Gln-NHMec Gln+NHMec S - - - Gln AMC - - - Monod et al., 2005
Hyp-NHMec Hyp+NHMec S - - - Hyp AMC - - - Monod et al., 2005
Hyp-NHMec Hyp+NHMec S - - - Hyp AMC - - - Monod et al., 2005
Leu-NHMec Leu+NHMec S - - - Leu AMC - - - Nakai & Yasuhara, 2004
Leu-NHMec Leu+NHMec S - - - Leu AMC - - - Monod et al., 2005
Leu-NHMec Leu+NHMec S - - - Leu AMC - - - Monod et al., 2005
Lys-Ala-NHMec Lys+Ala-NHMec S - - - Lys Ala AMC - - Nakai & Yasuhara, 2004
Lys-NHMec Lys+NHMec S - - - Lys AMC - - - Nakai & Yasuhara, 2004
Met-NHMec Met+NHMec S - - - Met AMC - - - Nakai & Yasuhara, 2004
Met-NHMec Met+NHMec S - - - Met AMC - - - Monod et al., 2005
Met-NHMec Met+NHMec S - - - Met AMC - - - Monod et al., 2005
Phe-NHMec Phe+NHMec S - - - Phe AMC - - - Nakai & Yasuhara, 2004
Phe-NHMec Phe+NHMec S - - - Phe AMC - - - Monod et al., 2005
Pro-NHMec Pro+NHMec S - - - Pro AMC - - - Nakai & Yasuhara, 2004
Pro-NHMec Pro+NHMec S - - - Pro AMC - - - Monod et al., 2005
Ser-NHMec Ser+NHMec S - - - Ser AMC - - - Nakai & Yasuhara, 2004
Ser-NHMec Ser+NHMec S - - - Ser AMC - - - Monod et al., 2005
Ser-NHMec Ser+NHMec S - - - Ser AMC - - - Monod et al., 2005
Tyr-NHMec Tyr+NHMec S - - - Tyr AMC - - - Nakai & Yasuhara, 2004