Substrates for peptidase M24.039: YdpF (Escherischia coli)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu	Ala+Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu	S	MS	-	-	-	Ala	Glu	Phe	Arg	His	Zheng et al., 2005
Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu	Ala+Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu	S	MS	-	-	-	Ala	Gly	Pro	His	Pro	Zheng et al., 2005
Ala-Ser	Ala+Ser	S	MS	-	-	-	Ala	Ser	-	-	-	Zheng et al., 2005
Ala-Thr-Val-Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Ala+Thr-Val-Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Ala	Thr	Val	Gly	Asp	Zheng et al., 2005
Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Asn+Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Asn	Thr	Asp	Arg	Pro	Zheng et al., 2005
Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu	Asp+Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu	S	MS	-	-	-	Asp	Ala	Glu	Phe	Arg	Zheng et al., 2005
Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Asp+Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Asp	Arg	Pro	Gly	Leu	Zheng et al., 2005
Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Asp+Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Asp	Val	Asn	Thr	Asp	Zheng et al., 2005
Gln-Ala-Thr-Val-Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Gln+Ala-Thr-Val-Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Gln	Ala	Thr	Val	Gly	Zheng et al., 2005
Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu	Glu+Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu	S	MS	-	-	-	Glu	Phe	Arg	His	Asp	Zheng et al., 2005
Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Gly+Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Gly	Asp	Val	Asn	Thr	Zheng et al., 2005
Lys-Ala-Arg-Val-Nle-NPh-Glu-Ala-Nle-NH2	Lys+Ala-Arg-Val-Nle-NPh-Glu-Ala-Nle-NH2	S	MS	-	-	-	Lys	Ala	Arg	Val	Nle	Zheng et al., 2005
Met-Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu	Met+Ala-Gly-Pro-His-Pro-Val-Ile-Val-Ile-Thr-Gly-Pro-His-Glu-Glu	S	MS	-	-	-	Met	Ala	Gly	Pro	His	Zheng et al., 2005
Met-Ala-Ser	Met+Ala-Ser	S	MS	-	-	-	Met	Ala	Ser	-	-	Zheng et al., 2005
Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Thr+Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Thr	Asp	Arg	Pro	Gly	Zheng et al., 2005
Thr-Val-Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Thr+Val-Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Thr	Val	Gly	Asp	Val	Zheng et al., 2005
Tyr-Leu-Leu-Pro-Ala-Glu-Val-Asn-Ile-Asp	Tyr+Leu-Leu-Pro-Ala-Glu-Val-Asn-Ile-Asp	S	MS	-	-	-	Tyr	Leu	Leu	Pro	Ala	Zheng et al., 2005
Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Val+Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Val	Asn	Thr	Asp	Arg	Zheng et al., 2005
Val-Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	Val+Gly-Asp-Val-Asn-Thr-Asp-Arg-Pro-Gly-Leu-Leu-Asp-Leu-Lys	S	MS	-	-	-	Val	Gly	Asp	Val	Asn	Zheng et al., 2005