Substrates for peptidase M24.008: hyperthermophile prolidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ala-Pro Ala+Pro S - - - Ala Pro - - - Adams & Grunden, 2004
Leu-Pro Leu+Pro S - - - Leu Pro - - - Adams & Grunden, 2004
Lys-Pro Lys+Pro S - - - Lys Pro - - - Are et al., 2017
Met-Pro Met+Pro S - - - Met Pro - - - Adams & Grunden, 2004
Met-Pro Met+Pro S - - - Met Pro - - - Are et al., 2017
Phe-Pro Phe+Pro S - - - Phe Pro - - - Adams & Grunden, 2004
Phe-Pro Phe+Pro S - - - Phe Pro - - - Are et al., 2017
Val-Pro Val+Pro S - - - Val Pro - - - Adams & Grunden, 2004