Substrates for peptidase M17.004: PepB aminopeptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Asp-Leu Asp+Leu N - - - Asp Leu - - - Mathew & Miller, 2004
Cys-Gly Cys+Gly P - - - Cys Gly - - - Suzuki et al., 2001
Cys-Leu Cys+Leu N - - - Cys Leu - - - Mathew & Miller, 2004
Glu-Leu Glu+Leu N - - - Glu Leu - - - Mathew & Miller, 2004
His-Leu His+Leu N - - - His Leu - - - Mathew & Miller, 2004
Leu-Leu Leu+Leu N - - - Leu Leu - - - Mathew & Miller, 2004
Met-Leu Met+Leu N - - - Met Leu - - - Mathew & Miller, 2004
microcin C7 Q47505 6-7 Ala+Asn P NT Thr Gly Asn Ala Asn - - - Kazakov et al., 2008