Substrates for peptidase M13.004: oligopeptidase O1

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
beta-casein P02666 208-224 Tyr-Gln-Glu-Pro+Val-Leu-Gly-Pro-Val-Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val P MS Tyr Gln Glu Pro Val Leu Gly Pro Soeryapranata et al., 2007
beta-casein P02666 208-224 Tyr-Gln-Glu-Pro-Val+Leu-Gly-Pro-Val-Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val P MS Gln Glu Pro Val Leu Gly Pro Val Soeryapranata et al., 2007
beta-casein P02666 208-224 Tyr-Gln-Glu-Pro-Val-Leu+Gly-Pro-Val-Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val P MS Glu Pro Val Leu Gly Pro Val Arg Soeryapranata et al., 2007
beta-casein P02666 208-224 Tyr-Gln-Glu-Pro-Val-Leu-Gly-Pro+Val-Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val P MS Val Leu Gly Pro Val Arg Gly Pro Soeryapranata et al., 2007
beta-casein P02666 208-224 Tyr-Gln-Glu-Pro-Val-Leu-Gly-Pro-Val+Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val P MS Leu Gly Pro Val Arg Gly Pro Phe Soeryapranata et al., 2007
beta-casein P02666 208-224 Tyr-Gln-Glu-Pro-Val-Leu-Gly-Pro-Val-Arg-Gly-Pro-Phe-Pro+Ile-Ile-Val P MS Gly Pro Phe Pro Ile Ile Val - Soeryapranata et al., 2007
beta-casein P02666 208-224 Tyr-Gln-Glu-Pro-Val-Leu-Gly-Pro-Val-Arg-Gly-Pro-Phe-Pro-Ile+Ile-Val P MS Pro Phe Pro Ile Ile Val - - Soeryapranata et al., 2007
Glt-Ala-Ala-Phe-4-methoxy-NHNap Glt-Ala-Ala+Phe-4-methoxy-NHNap S - Glt Ala Ala Phe MNA - - Mierau et al., 2004
Suc-Ala-Ala-Phe-4-methoxy-NHNap Suc-Ala-Ala+Phe-4-methoxy-NHNap S - Suc Ala Ala Phe MNA - - Mierau et al., 2004
Suc-Arg-Pro-Phe-His-Leu-Leu-Val-Tyr-NHMec Suc-Arg-Pro-Phe-His-Leu+Leu-Val-Tyr-NHMec S Pro Phe His Leu Leu Val Tyr AMC Mierau et al., 2004