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Peptidase

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Substrates for peptidase M12.191: antarease

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Hemopressin P01946 96-104 Pro-Val-Asn-Phe-Lys-Phe-Leu+Ser-His N Phe Lys Phe Leu Ser His - - Cajado Carvalho et al., 2014
Hemopressin P01946 96-104 Pro-Val-Asn-Phe-Lys-Phe+Leu-Ser-His N Asn Phe Lys Phe Leu Ser His - Cajado Carvalho et al., 2014
Hemopressin P01946 96-104 Pro-Val-Asn-Phe-Lys+Phe-Leu-Ser-His N Val Asn Phe Lys Phe Leu Ser His Cajado Carvalho et al., 2014
Hemopressin P01946 96-104 Pro-Val-Asn-Phe+Lys-Phe-Leu-Ser-His N Pro Val Asn Phe Lys Phe Leu Ser Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Pro63+Arg-Tyr P MS Leu Thr Arg Pro Arg Tyr '-' '-' Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Thr59+Leu-peptide P MS Tyr Ile Asn Thr Leu Thr Arg Pro Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Tyr56+Ile-peptide P MS Leu Arg Arg Tyr Ile Asn Thr Leu Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Arg55+Tyr-peptide P MS Gln Leu Arg Arg Tyr Ile Asn Thr Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Arg54+Arg-peptide P MS Thr Gln Leu Arg Arg Tyr Ile Asn Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Leu53+Arg-peptide P MS Glu Thr Gln Leu Arg Arg Tyr Ile Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Gln52+Leu-peptide P MS Tyr Glu Thr Gln Leu Arg Arg Tyr Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Thr51+Gln-peptide P MS Gln Tyr Glu Thr Gln Leu Arg Arg Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Tyr49+Glu-peptide P MS Arg Ala Gln Tyr Glu Thr Gln Leu Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Gln48+Tyr-peptide P MS Gln Arg Ala Gln Tyr Glu Thr Gln Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Ala47+Gln-peptide P MS Glu Gln Arg Ala Gln Tyr Glu Thr Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Glu44+Gln-peptide P MS Ala Thr His Glu Gln Arg Ala Gln Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Thr42+His-peptide P MS Asp Tyr Ala Thr His Glu Gln Arg Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Ala41+Thr-peptide P MS Gly Asp Tyr Ala Thr His Glu Gln Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Tyr40+Ala-peptide P MS Pro Gly Asp Tyr Ala Thr His Glu Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Asp39+Tyr-peptide P MS Tyr Pro Gly Asp Tyr Ala Thr His Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 Ala+Pro-peptide P MS '-' '-' '-' Ala Pro Leu Glu Pro Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Pro37+Gly-peptide P MS Pro Met Tyr Pro Gly Asp Tyr Ala Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Arg64+Tyr P MS Thr Arg Pro Arg Tyr '-' '-' '-' Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-Glu50+Thr-peptide P MS Ala Gln Tyr Glu Thr Gln Leu Arg Cajado Carvalho et al., 2014
pancreatic prohormone P06303 30-65 peptide-His43+Glu-peptide P MS Tyr Ala Thr His Glu Gln Arg Ala Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Ala40+Ser-peptide P MS Arg Glu Asp Ala Ser Pro Glu Glu Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Asp39+Ala-peptide P MS Pro Arg Glu Asp Ala Ser Pro Glu Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Glu38+Asp-peptide P MS Ala Pro Arg Glu Asp Ala Ser Pro Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Arg37+Glu-peptide P MS Glu Ala Pro Arg Glu Asp Ala Ser Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Pro36+Arg-peptide P MS Pro Glu Ala Pro Arg Glu Asp Ala Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Ala50+Ser-peptide P MS Arg Tyr Tyr Ala Ser Leu Arg His Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Ser51+Leu-peptide P MS Tyr Tyr Ala Ser Leu Arg His Tyr Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Arg61+Gln-Arg-Tyr P MS Leu Val Thr Arg Gln Arg Tyr '-' Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Arg63+Tyr P MS Thr Arg Gln Arg Tyr '-' '-' '-' Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Thr60+Arg-peptide P MS Asn Leu Val Thr Arg Gln Arg Tyr Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Tyr48+Tyr-peptide P MS Leu Asn Arg Tyr Tyr Ala Ser Leu Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Leu58+Val-peptide P MS Tyr Leu Asn Leu Val Thr Arg Gln Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Asn57+Leu-peptide P MS His Tyr Leu Asn Leu Val Thr Arg Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Tyr49+Ala-peptide P MS Asn Arg Tyr Tyr Ala Ser Leu Arg Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-Leu52+Arg-peptide P MS Tyr Ala Ser Leu Arg His Tyr Leu Cajado Carvalho et al., 2014
peptide YY {ECO:0000303|PubMed:2587421} P10082 29-64 peptide-His54+Tyr-peptide P MS Ser Leu Arg His Tyr Leu Asn Leu Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Arg48+Tyr-peptide P MS Asp Met Ala Arg Tyr Tyr Ser Ala Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 +Pro-peptide P MS '-' '-' '-' Tyr Pro Ser Lys Pro Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Asp40+Ala-peptide P MS Pro Gly Glu Asp Ala Pro Ala Glu Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 Tyr+Ser-peptide P MS '-' '-' Tyr Pro Ser Lys Pro Asp Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Gln63+Arg-Tyr P MS Ile Thr Arg Gln Arg Tyr '-' '-' Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Arg64+Tyr P MS Thr Arg Gln Arg Tyr '-' '-' '-' Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Arg62+Gln-Arg-Tyr P MS Leu Ile Thr Arg Gln Arg Tyr '-' Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Thr61+Arg-peptide P MS Asn Leu Ile Thr Arg Gln Arg Tyr Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Asn58+Leu-peptide P MS His Tyr Ile Asn Leu Ile Thr Arg Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Tyr56+Ile-peptide P MS Leu Arg His Tyr Ile Asn Leu Ile Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-His55+Tyr-peptide P MS Ala Leu Arg His Tyr Ile Asn Leu Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Ala52+Leu-peptide P MS Tyr Tyr Ser Ala Leu Arg His Tyr Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Ser51+Ala-peptide P MS Arg Tyr Tyr Ser Ala Leu Arg His Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Tyr50+Ser-peptide P MS Ala Arg Tyr Tyr Ser Ala Leu Arg Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Tyr49+Tyr-peptide P MS Met Ala Arg Tyr Tyr Ser Ala Leu Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Asp45+Met-peptide P MS Pro Ala Glu Asp Met Ala Arg Tyr Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Glu44+Asp-peptide P MS Ala Pro Ala Glu Asp Met Ala Arg Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Ala43+Glu-peptide P MS Asp Ala Pro Ala Glu Asp Met Ala Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Pro42+Ala-peptide P MS Glu Asp Ala Pro Ala Glu Asp Met Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Ala41+Pro-peptide P MS Gly Glu Asp Ala Pro Ala Glu Asp Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Glu39+Asp-peptide P MS Asn Pro Gly Glu Asp Ala Pro Ala Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Gly38+Glu-peptide P MS Asp Asn Pro Gly Glu Asp Ala Pro Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Asn36+Pro-peptide P MS Lys Pro Asp Asn Pro Gly Glu Asp Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Asp35+Asn-peptide P MS Ser Lys Pro Asp Asn Pro Gly Glu Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Leu53+Arg-peptide P MS Tyr Ser Ala Leu Arg His Tyr Ile Cajado Carvalho et al., 2014
pro-neuropeptide Y P07808 30-65 peptide-Arg54+His-peptide P MS Ser Ala Leu Arg His Tyr Ile Asn Cajado Carvalho et al., 2014
synaptobrevin 2 P63045 2-116 peptide-Leu84+Lys-peptide P MS Ala Ala Lys Leu Lys Arg Lys Tyr Fletcher et al., 2010
vesicle-associated membrane protein 8 Q9WUF4 1-74 peptide-Ala65+Arg-peptide P MS Gln Lys Val Ala Arg Lys Phe Trp Fletcher et al., 2010
vesicle-associated membrane protein 8 Q9WUF4 1-74 peptide-Arg66+Lys-peptide P MS Lys Val Ala Arg Lys Phe Trp Trp Fletcher et al., 2010

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