Substrates for peptidase M04.014: bacillolysin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
furylacryloyl-Gly-Leu-Ala furylacryloyl-Gly+Leu-Ala S - - FA Gly Leu Ala - - de Kreij et al., 2000
furylacryloyl-Gly-Leu-NH2 furylacryloyl-Gly+Leu-NH2 S - - FA Gly Leu NH2 - - de Kreij et al., 2000
furylacryloyl-Gly-Phe-Leu furylacryloyl-Gly+Phe-Leu S - - FA Gly Phe Leu - - de Kreij et al., 2000
furylacryloyl-Gly-Phe-NH2 furylacryloyl-Gly+Phe-NH2 S - - FA Gly Phe NH2 - - de Kreij et al., 2000
H-Phe-Gly-Gly-Leu-Ala H-Phe-Gly-Gly+Leu-Ala S - Phe Gly Gly Leu Ala - - Morihara & Tsuzuki, 1971
H-Phe-Gly-Leu-Ala H-Phe-Gly+Leu-Ala S - - Phe Gly Leu Ala - - Morihara & Tsuzuki, 1971
Metalloproteinase inhibitor P01077 1-131 Peptide-Cys39+Thr-Peptide P NT Gly Ser Leu Cys Thr Tyr Ser Gly Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Gly45+Leu-Peptide P NT Ser Gly Thr Gly Leu Ser Gly Ala Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Thr51+Val-Peptide P NT Gly Ala Arg Thr Val Ile Pro Ala Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Pro54+Ala-Peptide P NT Thr Val Ile Pro Ala Ser Asp Met Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Lys60+Ala-Peptide P NT Asp Met Glu Lys Ala Gly Thr Asp Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Lys67+Leu-Peptide P NT Asp Gly Val Lys Leu Pro Ala Ser Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Ser74+Phe-Peptide P NT Ser Ala Arg Ser Phe Ala Asn Gly Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-His80+Phe-Peptide P NT Asn Gly Thr His Phe Thr Leu Arg Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Thr82+Leu-Peptide P NT Thr His Phe Thr Leu Arg Tyr Gly Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Lys90+Val-Peptide P NT Pro Ala Arg Lys Val Thr Cys Val Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Cys93+Val-Peptide P NT Lys Val Thr Cys Val Arg Phe Pro Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Lys106+Val-Peptide P NT Thr Val Gly Lys Val Ala Pro Gly Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Gly110+Ala-Peptide P NT Val Ala Pro Gly Ala Gln Leu Arg Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Gln112+Leu-Peptide P NT Pro Gly Ala Gln Leu Arg Ser Leu Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Gly120+Ala-Peptide P NT Pro Ser Pro Gly Ala Thr Val Thr Tsuru et al., 1992
Metalloproteinase inhibitor P01077 1-131 Peptide-Thr124+Val-Peptide P NT Ala Thr Val Thr Val Gly Gln Asp Tsuru et al., 1992
regenerating islet-derived protein 3 alpha Q06141 27-175 peptide-Arg37+Ile-peptide N NT Pro Ser Ala Arg Ile Arg Cys Pro Medveczky et al., 2009
Z-Ala-Gly-Gly-Leu-Ala Z-Ala-Gly-Gly+Leu-Ala S Z Ala Gly Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-Ala-Gly-Leu-Ala Z-Ala-Gly+Leu-Ala S - Z Ala Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-Ala-Leu-Ala Z-Ala+Leu-Ala S - - Z Ala Leu Ala - - Morihara & Tsuzuki, 1971
Z-D-Ala-Gly-Gly-Leu-Ala Z-D-Ala-Gly-Gly+Leu-Ala S Z DAl Gly Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-D-Ala-Gly-Leu-Ala Z-D-Ala-Gly+Leu-Ala S - Z DAl Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-Gly-Gly-Leu-Ala Z-Gly-Gly+Leu-Ala S - Z Gly Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-Gly-Leu-Ala Z-Gly+Leu-Ala S - - Z Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-Gly-Leu-Gly-Ala Z-Gly+Leu-Gly-Ala S - - Z Gly Leu Gly Ala - Morihara & Tsuzuki, 1971
Z-Gly-Leu-Gly-Phe Z-Gly+Leu-Gly-Phe S - - Z Gly Leu Gly Phe - Morihara & Tsuzuki, 1971
Z-Gly-Leu-Leu Z-Gly+Leu-Leu S - - Z Gly Leu Leu - - Morihara & Tsuzuki, 1971
Z-Gly-Leu-Phe Z-Gly+Leu-Phe S - - Z Gly Leu Phe - - Morihara & Tsuzuki, 1971
Z-Phe-Ala-Ala Z-Phe+Ala-Ala S - - Z Phe Ala Ala - - Morihara & Tsuzuki, 1971
Z-Phe-Gly-Gly-Leu-Ala Z-Phe-Gly-Gly+Leu-Ala S Z Phe Gly Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-Phe-Gly-Leu-Ala Z-Phe-Gly+Leu-Ala S - Z Phe Gly Leu Ala - - Morihara & Tsuzuki, 1971
Z-Phe-Ile-Ala Z-Phe+Ile-Ala S - - Z Phe Ile Ala - - Morihara & Tsuzuki, 1971
Z-Phe-Leu-Ala Z-Phe+Leu-Ala S - - Z Phe Leu Ala - - Morihara & Tsuzuki, 1971
Z-Phe-Phe-Ala Z-Phe+Phe-Ala S - - Z Phe Phe Ala - - Morihara & Tsuzuki, 1971
Z-Phe-Val-Ala Z-Phe+Val-Ala S - - Z Phe Val Ala - - Morihara & Tsuzuki, 1971