Substrates for peptidase M04.011: lambda toxin

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
epsilon-toxin Q02307 46-328 peptide-Tyr267+Val-peptide P Val Gln Glu Tyr Val Ile Pro Val Okabe & Matsushita, 2004 16486
epsilon-toxin precursor Q02307 32-328 peptide-Glu10+Met-peptide P Val Ser Asn Glu Met Ser Lys Lys Okabe & Matsushita, 2004 16485
iota-toxin Ia precursor peptide-Tyr37+Ile-peptide N Ala Ser Asn Tyr Ile Thr Asp Arg Okabe & Matsushita, 2004
iota-toxin Ib precursor peptide-Ser210+Ala-peptide N Arg Phe Phe Ser Ala Ala Trp Glu Okabe & Matsushita, 2004