Substrates for peptidase C60.002: sortase B

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Abz-Lys-Val-Glu-Asn-Pro-Gln-Thr-Asn-Ala-Gly-Thr-Dap(DNP)-NH2 Peptide-Thr+Asn-Ala-Gly-Thr S Asn Pro Gln Thr Asn Ala Gly Thr Bentley et al., 2007
iron-regulated surface determinant protein C Q8KQR1 29-227 peptide-Thr192+Asn-peptide P CS Asn Pro Gln Thr Asn Ala Gly Thr Mazmanian et al., 2002
lmo2185 protein Q9KGV9 1-569 peptide-Thr539+Asn-peptide P MU Asn Ala Lys Thr Asn Asp Ser Ser Mariscotti et al., 2009
lmo2186 protein Q8Y585 1-207 peptide-Ser177+Ser-peptide P MU Asn Pro Lys Ser Ser Asp Ser Ser Mariscotti et al., 2009
putative LPXTG-motif cell wall anchor domain protein Q81L43 1-237 peptide-Thr209+Gly-peptide P CS Asn Pro Lys Thr Gly Asp Glu Ala Gaspar et al., 2005