Substrates for peptidase C58.001: YopT peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
cell division control protein 42 homolog, Isoform 1	P60953-1	1-188	peptide-Lys187+Cys-Cys-Ile-Phe	P	Pro	Lys	Arg	Lys	Cys	Cys	Ile	Phe	Shao et al., 2003	21153
ras-related C3 botulinum toxin substrate 1	P63000	1-189	peptide-Lys188+Cys-Leu-Leu-Leu	P	Arg	Lys	Arg	Lys	Cys	Leu	Leu	Leu	Shao et al., 2003	21151
transforming protein RhoA precursor	P61586	1-190	peptide-Gly189+Cys-Leu-Val-Leu	P	Lys	Lys	Ser	Gly	Cys	Leu	Val	Leu	Shao et al., 2003	18014