Substrates for peptidase C46.004: Desert hedgehog protein

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Desert hedgehog protein Q61488 23-296 peptide-Gly198+Cys-peptide P CS Arg Ala Gly Gly Cys Phe Pro Gly Kumar et al., 1996
desert hedgehog protein O43323 23-396 peptide-Gly198+Cys-peptide N Arg Ala Gly Gly Cys Phe Pro Gly