Substrates for peptidase C32.001: equine arteritis virus-type cysteine peptidase

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
equine arteritis virus Nsp2-type cysteine peptidase	Q06502	1-3637	peptide-Tyr380+Gly-peptide	P		Arg	Lys	Tyr	Tyr	Gly	Tyr	Ser	Pro	Snijder et al., 2004	16331
Equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Gly260+Gly-peptide	P	CS	Gly	Asn	Tyr	Gly	Gly	Tyr	Asn	Pro	Ziebuhr et al., 2000
Lactate dehydrogenase elevating virus ORF1ab polyprotein	Q83017	1-3616	peptide-Tyr380+Gly-peptide	P	CS	Arg	Lys	Tyr	Tyr	Gly	Tyr	Ser	Pro	Den Boon et al., 1995
polyprotein 1A	Q9WJB2	1-3960	peptide-Tyr382+Gly-peptide	P		His	Lys	Trp	Tyr	Gly	Ala	Gly	Lys	Snijder et al., 2004	16332
Replicase polyprotein 1ab	P19811	1-3175	peptide-Gly260+Gly-peptide	P		Gly	Asn	Tyr	Gly	Gly	Tyr	Asn	Pro	Snijder et al., 2004	16330