Substrates for peptidase C16.005: avian infectious bronchitis coronavirus papain-like peptidase

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB	MERNUM
replicase polyprotein 1ab	P0C6Y1	1-6629	peptide-Gly673+Gly-peptide	P	MU	Cys	Lys	Ala	Gly	Gly	Lys	Thr	Val	Lim & Liu, 1998	16265
replicase polyprotein 1ab	P0C6Y1	1-6629	peptide-Gly2265+Gly-peptide	P	MU	Lys	Lys	Ala	Gly	Gly	Ile	Val	Ser	Lim et al., 2000	16264