Substrates for peptidase C14.050: orthocaspase MaOC1 (Microcystis aeruginosa)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Boc-Gly-Arg-Arg-NHMec			Boc-Gly-Arg-Arg+NHMec	S		Boc	Gly	Arg	Arg	AMC	-	-	-	Klemencic et al., 2015
Boc-Gly-Lys-Arg-NHMec			Boc-Gly-Lys-Arg+NHMec	S		Boc	Gly	Lys	Arg	AMC	-	-	-	Klemencic et al., 2015
Boc-Val-Leu-Lys-NHMec			Boc-Val-Leu-Lys+NHMec	S		Boc	Val	Leu	Lys	AMC	-	-	-	Klemencic et al., 2015
microcystis aeruginosa PCC 7806 genome sequencing data, contig C328 {ECO:0000313\|EMBL:CAO88281.1}	A8YMU3	1-698	peptide-Arg5+Gln-peptide	P	NT	Thr	Asp	Ser	Arg	Gln	Lys	Ser	Pro	Klemencic et al., 2015
microcystis aeruginosa PCC 7806 genome sequencing data, contig C328 {ECO:0000313\|EMBL:CAO88281.1}	A8YMU3	1-698	peptide-Arg219+Asn-peptide	P	NT	Thr	Pro	Thr	Arg	Asn	Leu	Ala	Val	Klemencic et al., 2015
Z-Arg-Arg-NHMec			Z-Arg-Arg+NHMec	S		-	Z	Arg	Arg	AMC	-	-	-	Klemencic et al., 2015
Z-Leu-Arg-NHMec			Z-Leu-Arg+NHMec	S		-	Z	Leu	Arg	AMC	-	-	-	Klemencic et al., 2015
Z-Phe-Arg-NHMec			Z-Phe-Arg+NHMec	S		-	Z	Phe	Arg	AMC	-	-	-	Klemencic et al., 2015
Z-Val-Val-Arg-NHMec			Z-Val-Val-Arg+NHMec	S		Z	Val	Val	Arg	AMC	-	-	-	Klemencic et al., 2015