Substrates for peptidase C14.049: metacaspase Atmc5 (Arabidopsis sp.)

Summary Gene structure Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Boc-Gly-Arg-Arg-NHMec Boc-Gly-Arg-Arg+NHMec S Boc Gly Arg Arg AMC - - - Watanabe & Lam, 2005
Boc-Val-Leu-Lys-MCA Boc-Val-Leu-Lys+MCA S CS Boc Val Leu Lys MCA - - - Watanabe & Lam, 2005
Z-Ala-Arg-Arg-NHNap Z-Ala-Arg-Arg+NHNap S Z Ala Arg Arg NAP - - - Watanabe & Lam, 2005
Z-Arg-Arg-NHNap Z-Arg-Arg+NHNap S - Z Arg Arg NAP - - - Watanabe & Lam, 2005
Z-Arg-NHNap Z-Arg+NHNap S - - Z Arg NAP - - - Watanabe & Lam, 2005
Z-Gly-Arg-Arg-NHNap Z-Gly-Arg-Arg+NHNap S Z Gly Arg Arg NAP - - - Watanabe & Lam, 2005
Z-Gly-Gly-Arg-NHNap Z-Gly-Gly-Arg+NHNap S Z Gly Gly Arg NAP - - - Watanabe & Lam, 2005
Z-Val-Leu-Lys-NHNap Z-Val-Leu-Lys+NHNap S Z Val Leu Lys NAP - - - Watanabe & Lam, 2005
Z-Val-Lys-Lys-Arg-NHNap Z-Val-Lys-Lys-Arg+NHNap S Val Lys Lys Arg NAP - - - Watanabe & Lam, 2005