Substrates for peptidase C11.003: PmC11 peptidase (Parabacteroides merdae)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ac-Val-Leu-Gly-Lys-NHMec Ac-Val-Leu-Gly-Lys+NHMec S Val Leu Gly Lys AMC - - - Roncase et al., 2017
Ac-Val-Leu-Thr-Lys-NHMec Ac-Val-Leu-Thr-Lys+NHMec S Val Leu Thr Lys AMC - - - Roncase et al., 2017
Boc-Val-Leu-Lys-NHMec Boc-Val-Leu-Lys+NHMec S Boc Val Leu Lys AMC - - - McLuskey et al., 2016
Bz-Arg-NHMec Bz-Arg+NHMec S - - Bz Arg AMC - - - McLuskey et al., 2016
clostripain family R6WL17 1-375 peptide-Lys147+Ala-peptide P NT Asn Lys Leu Lys Ala Phe Gly Gln McLuskey et al., 2016
clostripain family R6WL17 1-375 peptide-Lys250+Thr-peptide P MS Ser Leu Thr Lys Thr Ser Glu Leu Roncase et al., 2017
Z-Gly-Gly-Arg-NHMec Z-Gly-Gly-Arg+NHMec S Z Gly Gly Arg AMC - - - McLuskey et al., 2016