Substrates for peptidase C03.012: tomato ringspot nepovirus picornain 3C

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
rNA1 polyprotein P29150 1-2197 peptide-Gln423+Gly-peptide P MU His Ala Ala Gln Gly Phe Gly Asn Wang & Sanfacon, 2000
rNA1 polyprotein P29150 1-2197 peptide-Gln620+Gly-peptide P MU Ala Pro Thr Gln Gly Leu Thr Asp Wang & Sanfacon, 2000
rNA1 polyprotein P29150 1-2197 peptide-Gln1239+Gly-peptide P NT Gln Ser Val Gln Gly Ser Ser Leu Wang et al., 1999
rNA1 polyprotein P29150 1-2197 peptide-Gln1212+Ser-peptide P NT Met Thr Val Gln Ser Thr Ile Pro Wang et al., 1999
rNA1 polyprotein P29150 1-2197 peptide-Gln1486+Ser-peptide P NT Ala Pro Cys Gln Ser Ser Val Ile Wang et al., 1999
rNA2 polyprotein P25247 1-1882 peptide-Gln934+Ser-peptide P NT Ser Asn Cys Gln Ser Ser Leu Gly Wang & Sanfacon, 2000
rNA2 polyprotein P25247 1-1882 peptide-Gln1320+Gly-peptide P NT Ser Ser Val Gln Gly Gly Ser Trp Hans & Sanfacon, 1995