Substrates for peptidase C03.009: cardiovirus picornain 3C

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
polyprotein P03304 1-2290 peptide-Gln67+Gly-peptide P Phe Glu Leu Gln Gly Asn Ser Thr Skern, 2004 16159
polyprotein P03304 1-2290 peptide-Gln391+Gly-peptide P Leu Ser Arg Gln Ser Pro Ile Pro Skern, 2004 16157
polyprotein P03304 1-2290 peptide-Gln622+Gly-peptide P Trp Ser Pro Gln Gly Val Glu Asn Skern, 2004 16158
polyprotein P03304 1-2290 peptide-Gln1192+Gly-peptide P Phe Gln Gln Gln Ser Pro Leu Lys Skern, 2004 16152
polyprotein P03304 1-2290 peptide-Gln1517+Gly-peptide P Leu Val Ala Gln Gly Pro Val Asp Skern, 2004 16153
polyprotein P03304 1-2290 peptide-Gln1605+Gly-peptide P Glu Gln Glu Gln Gly Pro Tyr Asn Skern, 2004 16154
polyprotein P03304 1-2290 peptide-Gln1625+Gly-peptide P Leu Asp Ile Gln Gly Pro Asn Pro Skern, 2004 16155
polyprotein P03304 1-2290 peptide-Gln1830+Gly-peptide P Phe Glu Pro Gln Gly Ala Leu Glu Skern, 2004 16156
polyprotein P03304 1-2290 peptide-Gln1056+Gly-peptide P Phe Gln Thr Gln Gly Ala Ala Val Skern, 2004 16151