Substrates for peptidase C01.057: vinckepain-2

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Abz-Asp-Val-Thi-Gly-Tyr(NO2)-Glu-NH2	Abz-Asp-Val-Thi+Gly-Tyr(NO2)-Glu-NH2	S	Asp	Val	Thi	Gly	Tyn	Glu	NH2	-	Ramjee et al., 2006
Abz-Asp-Val-Thr-Gly-Tyr(NO2)-Glu-NH2	Abz-Asp-Val-Thr+Gly-Tyr(NO2)-Glu-NH2	S	Asp	Val	Thr	Gly	Tyn	Glu	NH2	-	Ramjee et al., 2006
Abz-Ile-Leu-Lys-Ala-Tyr(NO2)-Glu-NH2	Abz-Ile-Leu-Lys+Ala-Tyr(NO2)-Glu-NH2	S	Abz	Ile	Leu	Lys	Ala	Tyn	Glu	NH2	Ramjee et al., 2006
Abz-Ile-Leu-Lys-Arg-Tyr(NO2)-Glu-NH2	Abz-Ile-Leu-Lys+Arg-Tyr(NO2)-Glu-NH2	S	Abz	Ile	Leu	Lys	Arg	Tyn	Glu	NH2	Ramjee et al., 2006
Abz-Ile-Leu-Lys-Leu-Tyr(NO2)-Glu-NH2	Abz-Ile-Leu-Lys+Leu-Tyr(NO2)-Glu-NH2	S	Abz	Ile	Leu	Lys	Leu	Tyn	Glu	NH2	Ramjee et al., 2006
Abz-Ile-Leu-Thr-Gly-Tyr(NO2)-Glu-NH2	Abz-Ile-Leu-Thr+Gly-Tyr(NO2)-Glu-NH2	S	Ile	Leu	Thr	Gly	Tyn	Glu	NH2	-	Ramjee et al., 2006
Abz-Ile-Val-Thi-Gly-Tyr(NO2)-Glu-NH2	Abz-Ile-Val-Thi+Gly-Tyr(NO2)-Glu-NH2	S	Ile	Leu	Thi	Gly	Tyn	Glu	NH2	-	Ramjee et al., 2006
Abz-Ile-Val-Thr-Gly-Tyr(NO2)-Glu-NH2	Abz-Ile-Val-Thr+Gly-Tyr(NO2)-Glu-NH2	S	Ile	Val	Thr	Gly	Tyn	Glu	NH2	-	Ramjee et al., 2006
Abz-Leu-Arg-Phe-Pro-Tyr(NO2)-Glu-NH2	Abz-Leu-Arg+Phe-Pro-Tyr(NO2)-Glu-NH2	S	-	Abz	Leu	Arg	Phe	Pro	Tyn	Glu	Ramjee et al., 2006
Abz-Leu-Leu-Arg-Ala-Tyr(NO2)-Glu-NH2	Abz-Leu-Leu-Arg+Ala-Tyr(NO2)-Glu-NH2	S	Abz	Leu	Leu	Arg	Ala	Tyn	Glu	NH2	Ramjee et al., 2006
Abz-Leu-Leu-Thi-Ala-Tyr(NO2)-Glu-NH2	Abz-Leu-Leu-Thi+Ala-Tyr(NO2)-Glu-NH2	S	Abz	Leu	Leu	Thi	Ala	Tyn	Glu	NH2	Ramjee et al., 2006
Abz-Leu-Leu-Thi-Arg-Tyr(NO2)-Glu-NH2	Abz-Leu-Leu-Thi+Arg-Tyr(NO2)-Glu-NH2	S	Abz	Leu	Leu	Thi	Arg	Tyn	Glu	NH2	Ramjee et al., 2006
Abz-Leu-Tyr-Arg-Ala-Tyr(NO2)-Glu-NH2	Abz-Leu-Tyr-Arg+Ala-Tyr(NO2)-Glu-NH2	S	Abz	Leu	Tyr	Arg	Ala	Tyn	Glu	NH2	Ramjee et al., 2006
Abz-Leu-Val-Thi-Gly-Tyr(NO2)-Glu-NH2	Abz-Leu-Val-Thi+Gly-Tyr(NO2)-Glu-NH2	S	Ile	Val	Thi	Gly	Tyn	Glu	NH2	-	Ramjee et al., 2006
Ac-Asp-Glu-Val-Asp-NHMec	Ac-Asp-Glu-Val-Asp+NHMec	S	Asp	Glu	Val	Asp	AMC	-	-	-	Ramjee et al., 2006
Ac-Asp-Glu-Val-Asp-NHMec	Ac-Asp-Glu-Val-Asp+NHMec	S	Asp	Glu	Val	Asp	AMC	-	-	-	Ramjee et al., 2006
Boc-Val-Leu-Lys-NHMec	Boc-Val-Leu-Lys+NHMec	S	Boc	Val	Leu	Lys	AMC	-	-	-	Singh et al., 2002
Boc-Val-Leu-Lys-NHMec	Boc-Val-Leu-Lys+NHMec	S	Boc	Val	Leu	Lys	AMC	-	-	-	Ramjee et al., 2006
Bz-Phe-Val-Arg-NHMec	Bz-Phe-Val-Arg+NHMec	S	Bz	Phe	Val	Arg	AMC	-	-	-	Singh et al., 2002
Bz-Phe-Val-Arg-NHMec	Bz-Phe-Val-Arg+NHMec	S	Bz	Phe	Val	Arg	AMC	-	-	-	Ramjee et al., 2006
Z-Leu-Arg-NHMec	Z-Leu-Arg+NHMec	S	-	Z	Leu	Arg	AMC	-	-	-	Singh et al., 2002
Z-Leu-Arg-NHMec	Z-Leu-Arg+NHMec	S	-	Z	Leu	Arg	AMC	-	-	-	Ramjee et al., 2006
Z-Leu-Leu-Arg-NHMec	Z-Leu-Leu-Arg+NHMec	S	Z	Val	Leu	Arg	AMC	-	-	-	Singh et al., 2002
Z-Phe-Arg-NHMec	Z-Phe-Arg+NHMec	S	-	Z	Phe	Arg	AMC	-	-	-	Singh et al., 2002
Z-Val-Arg-NHMec	Z-Val-Arg+NHMec	S	-	Z	Val	Arg	AMC	-	-	-	Singh et al., 2002
Z-Val-Leu-Arg-NHMec	Z-Val-Leu-Arg+NHMec	S	Z	Val	Leu	Arg	AMC	-	-	-	Singh et al., 2002
Z-Val-Leu-Arg-NHMec	Z-Val-Leu-Arg+NHMec	S	Z	Val	Leu	Arg	AMC	-	-	-	Ramjee et al., 2006
Z-Val-Val-Arg-NHMec	Z-Val-Val-Arg+NHMec	S	Z	Val	Val	Arg	AMC	-	-	-	Singh et al., 2002