Substrates for peptidase C01.027: comosain

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Arg-Ala	Arg+Ala	S	-	-	-	Arg	Ala	-	-	-	Napper et al., 1994
Arg-Ser	Arg-Ser	S	-	-	-	Arg	Ser	-	-	-	Napper et al., 1994
Arg-Thr	Arg+Thr	S	-	-	-	Arg	Thr	-	-	-	Napper et al., 1994
Asn-Ala	Asn+Ala	S	-	-	-	Asn	Ala	-	-	-	Napper et al., 1994
Asn-Ser	Asn+Ser	S	-	-	-	Asn	Ser	-	-	-	Napper et al., 1994
Asn-Thr	Asn+Thr	S	-	-	-	Asn	Thr	-	-	-	Napper et al., 1994
Glu-Ala	Glu+Ala	S	-	-	-	Glu	Ala	-	-	-	Napper et al., 1994
Glu-Ser	Glu+Ser	S	-	-	-	Glu	Ser	-	-	-	Napper et al., 1994
Glu-Thr	Glu+Thr	S	-	-	-	Glu	Thr	-	-	-	Napper et al., 1994
Lys-Ala	Lys+Ala	S	-	-	-	Lys	Ala	-	-	-	Napper et al., 1994
Lys-Ser	Lys+Ser	S	-	-	-	Lys	Ser	-	-	-	Napper et al., 1994
Lys-Thr	Lys+Thr	S	-	-	-	Lys	Thr	-	-	-	Napper et al., 1994
Z-Arg-Arg-NHMec	Z-Arg-Arg+NHMec	S	-	Z	Arg	Arg	AMC	-	-	-	Rowan, 2004