Substrates for peptidase A31.001: HybD peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
hydrogenase-1 large chain	P0ACD8	1-597	peptide-His582+Val-peptide	P	Cys	Ser	Thr	His	Val	Leu	Gly	Asp	Theodoratou et al., 2000
hydrogenase-2 large chain precursor	P0ACE0	2-552	peptide-His551+Val-peptide	N	Cys	Ala	Val	His	Val	Val	Asp	Ala
hydrogenase-2 large chain precursor	P0ACE0	2-567	peptide-His551+Val-peptide	P	Cys	Ala	Val	His	Val	Val	Asp	Ala	Theodoratou et al., 2000
periplasmic [NiFe] hydrogenase large subunit precursor	P12944	2-551	peptide-His535+Val-peptide	P	Cys	Gly	Val	His	Val	Ile	Asp	Pro	Menon et al., 1993