Merops Switch to
Inhibitors

Peptidase

Family Clan SEARCHES BLAST
MEROPS SUBMISSIONS

Other
information

Substrates for peptidase A25.001: gpr peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
gpr peptidase precursor P22321 1-371 peptide-Asp15+Leu-peptide N Val Arg Thr Asp Leu Ala Val Glu Setlow, 2004
small acid soluble protein-alpha P04831 1-69 Met-Lys-Leu-Glu+Ile-Ala-Ser-Glu-Phe N Met Lys Leu Glu Ile Ala Ser Glu Setlow, 2004
small acid soluble protein-gamma P07784 1-84 Phe-Gly-Thr-Glu+Phe-Ala-Ser-Glu-Thr N Phe Gly Thr Glu Phe Ala Ser Glu Setlow, 2004
small, acid-soluble spore protein 1 P41371 2-60 peptide-Glu18+Val-peptide N Phe Lys Asn Glu Val Ala Arg Glu
small, acid-soluble spore protein 1 P0A4F3 1-70 peptide-Glu27+Ile-peptide N Met Lys Tyr Glu Ile Ala Gln Glu
small, acid-soluble spore protein 1 P06552 1-70 peptide-Glu28+Ile-peptide N Met Lys Phe Glu Ile Ala Ser Glu
small, acid-soluble spore protein 1 Q00213 1-72 peptide-Glu25+Ile-peptide N Met Lys Tyr Glu Ile Ala Gln Glu
small, acid-soluble spore protein 1 P52968 1-69 peptide-Glu27+Ile-peptide N Met Lys Glu Glu Ile Ala Asn Glu
small, acid-soluble spore protein 1 P06553 1-71 peptide-Glu28+Ile-peptide N Met Lys Phe Glu Ile Ala Gln Glu
small, acid-soluble spore protein 2 P0A4F5 1-65 peptide-Glu23+Ile-peptide N Met Lys Tyr Glu Ile Ala Gln Glu
small, acid-soluble spore protein 2 P0A4F4 1-65 peptide-Glu23+Ile-peptide N Met Lys Tyr Glu Ile Ala Gln Glu
small, acid-soluble spore protein 2 P52969 1-67 peptide-Glu25+Ile-peptide N Met Lys Glu Glu Ile Ala Ser Glu
small, acid-soluble spore protein A P02959 2-62 peptide-Glu21+Ile-peptide N Met Lys Tyr Glu Ile Ala Ser Glu
small, acid-soluble spore protein alpha P22065 1-70 peptide-Glu23+Ile-peptide N Met Lys Leu Glu Ile Ala Asn Glu
small, acid-soluble spore protein B P04832 1-67 peptide-Glu25+Ile-peptide N Met Lys Leu Glu Ile Ala Ser Glu
small, acid-soluble spore protein beta P22066 1-64 peptide-Glu19+Ile-peptide N Met Lys Leu Glu Ile Ala Asn Glu
small, acid-soluble spore protein C P02958 1-72 peptide-Glu30+Ile-peptide N Met Lys Leu Glu Ile Ala Ser Glu
small, acid-soluble spore protein C P02960 2-72 peptide-Glu30+Ile-peptide N Met Lys Phe Glu Ile Ala Ser Glu
small, acid-soluble spore protein C1 P10570 1-69 peptide-Glu27+Ile-peptide N Met Lys Tyr Glu Ile Ala Ser Glu
small, acid-soluble spore protein C1 P21886 2-59 peptide-Glu19+Val-peptide N Phe Lys Asn Glu Val Ala Ala Glu
small, acid-soluble spore protein C2 P10571 1-73 peptide-Glu27+Ile-peptide N Met Lys Tyr Glu Ile Ala Ser Glu
small, acid-soluble spore protein C2 P21887 2-60 peptide-Glu18+Val-peptide N Phe Lys Asn Glu Val Ala Asn Glu
small, acid-soluble spore protein C3 P10572 1-65 peptide-Glu22+Ile-peptide N Tyr Lys Tyr Glu Ile Ala Gln Glu
small, acid-soluble spore protein C4 P04834 1-69 peptide-Glu27+Ile-peptide N Met Lys Tyr Glu Ile Ala Ser Glu
small, acid-soluble spore protein C5 P04835 1-73 peptide-Glu27+Ile-peptide N Met Lys Tyr Glu Ile Ala Ser Glu
small, acid-soluble spore protein D P04833 2-64 peptide-Glu21+Val-peptide N Phe Lys Leu Glu Val Ala Gln Glu
small, acid-soluble spore protein gamma-type P07787 1-93 peptide-Glu27+Phe-peptide N Tyr Gly Thr Glu Phe Ser Thr Glu
small, acid-soluble spore protein gamma-type P07787 1-93 peptide-Glu64+Phe-peptide N Tyr Gly Thr Glu Phe Ala Thr Glu
small, acid-soluble spore protein gamma-type P02961 2-97 peptide-Glu32+Phe-peptide N Phe Gly Thr Glu Phe Gly Ser Glu
small, acid-soluble spore protein gamma-type P02961 2-97 peptide-Glu67+Phe-peptide N Phe Gly Thr Glu Phe Ala Ser Glu
small, acid-soluble spore protein gamma-type P07785 1-82 peptide-Glu30+Phe-peptide N Phe Gly Thr Glu Phe Ala Ser Glu
small, acid-soluble spore protein gamma-type P07786 1-96 peptide-Glu36+Phe-peptide N Phe Ala Thr Glu Phe Ala Ser Glu

feedback
Page created 8-September-2023

EMBL-EBI logo

© 2025 EBI
Terms of use