Substrates for peptidase A24.001: type 4 prepilin peptidase 1

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
bundle-forming pilus, structural subunit precursor	P33553	1-193	peptide-Gly13+Leu-peptide	P		Tyr	Glu	Lys	Gly	Leu	Ser	Leu	Ile	Dupuy et al., 2004	16068
Fimbrial protein Q	P07640	1-157	peptide-Gly6+Phe-peptide	P	CS	Ala	Gln	Lys	Gly	Phe	Thr	Leu	Ile	Nunn & Lory, 1991
General secretion pathway protein H	H3LWR8	1-170	Peptide-Gly5+Phe-Peptide	P	CS	Arg	Gln	Arg	Gly	Phe	Thr	Leu	Leu	Strom & Lory, 1992
toxin co-regulated pilin precursor	P23024	1-224	peptide-Gly25+Met-peptide	P		Gly	Gln	Glu	Gly	Met	Thr	Leu	Leu	Dupuy et al., 2004	16069
type 4 fimbrial biogenesis protein PilV	Q57003	1-185	peptide-Gly14+Leu-peptide	P		His	Gln	Ser	Gly	Phe	Ser	Met	Ile	Dupuy et al., 2004	16070
type 4 pilin precursor	P20657	1-159	Met-Asn-Ala-Gln-Lys-Gly+Phe-peptide	P		Ala	Gln	Lys	Gly	Phe	Thr	Leu	Ile	Strom & Lory, 1991
type 4 pilin precursor	P04739	1-149	Met-Lys-Ala-Gln-Lys-Gly+Phe-peptide	P		Ala	Gln	Lys	Gly	Phe	Thr	Leu	Ile	Strom & Lory, 1991	16074
type 4 pilin precursor	P02974	1-165	Met-Asn-Thr-Leu-Gln-Lys-Gly+Phe-peptide	P		Leu	Gln	Lys	Gly	Phe	Thr	Leu	Ile	Strom & Lory, 1991
type 4 pilin precursor	P04953	1-156	Met-Lys-Ser-Leu-Gln-Lys-Gly+Phe-peptide	P		Leu	Gln	Lys	Gly	Phe	Thr	Leu	Ile	Strom & Lory, 1991	16073
Type II secretion system protein G	Q00514	1-142	peptide-Gly8+Phe-peptide	P	CS	Gln	Gln	Ser	Gly	Phe	Thr	Leu	Ile	Nunn & Lory, 1992
Type II secretion system protein G	P15746	1-140	peptide-Gly6+Phe-peptide	P	CS	Arg	Gln	Arg	Gly	Phe	Thr	Leu	Leu	Nunn & Lory, 1991
Type II secretion system protein H	Q00515	1-172	peptide-Gly6+Phe-peptide	P	CS	Ala	Ser	Arg	Gly	Phe	Thr	Leu	Ile	Nunn & Lory, 1992
Type II secretion system protein I	Q00516	1-129	peptide-Gly6+Phe-peptide	P	DF	Arg	Ala	Arg	Gly	Phe	Thr	Leu	Leu	Nunn & Lory, 1992
Type II secretion system protein I	P15748	1-121	Peptide-Gly6+Met-Peptide	P	CS	Lys	Gln	Ser	Gly	Met	Thr	Leu	Ile	Nunn & Lory, 1991
Type II secretion system protein J	Q00517	1-237	peptide-Gly6+Phe-peptide	P	CS	Leu	Gln	Arg	Gly	Phe	Thr	Leu	Leu	Nunn & Lory, 1992
Type II secretion system protein J	P15749	1-198	Peptide-Gly7+Phe-Peptide	P	CS	Arg	Ser	Ser	Gly	Phe	Thr	Leu	Val	Nunn & Lory, 1991