Substrates for peptidase A02.063: walleye dermal sarcoma virus retropepsin

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
gag polyprotein	Q88937	1-582	peptide-Met95+Thr-peptide	P		Ala	Arg	Gln	Met	Thr	Ala	His	Thr	Fodor & Vogt, 2002	16018
gag polyprotein	Q88937	1-582	peptide-His251+Pro-peptide	P		Gln	Tyr	Gln	His	Pro	Ile	Arg	Asn	Fodor & Vogt, 2002	16017
gag polyprotein	Q9WHI6	1-534	peptide-Lys198+Pro-peptide	P		Phe	Pro	Gln	Lys	Pro	Val	Arg	His	Fodor & Vogt, 2002	16020
gag polyprotein	Q9WHJ1	1-522	peptide-Leu194+Pro-peptide	P		Val	His	Gln	Leu	Pro	Ile	Arg	Asn	Fodor & Vogt, 2002	16021
gag polyprotein	Q9WHI6	1-534	peptide-Leu404+Ala-peptide	P		Val	Val	Gln	Leu	Ala	Val	Pro	Asn	Fodor & Vogt, 2002	16019
gag polyprotein	Q9WHJ1	1-522	peptide-Leu400+Ala-peptide	P		Val	Val	Gln	Leu	Ala	Ile	Pro	Asn	Fodor & Vogt, 2002	16022
Phe-Leu-Val-Gln-Arg-Val-Leu-Lys-Lys-Gly			Phe-Leu-Val-Gln-Arg+Val-Leu-Lys-Lys-Gly	N		Leu	Val	Gln	Arg	Val	Leu	Lys	Lys	Fodor & Vogt, 2002
polyprotein	A4GTG2	1-1751	peptide-Leu457+Ala-peptide	P		Val	Leu	Gln	Leu	Ala	Met	Pro	Ala	Fodor & Vogt, 2002	16024
polyprotein	A4GTG2	1-1751	peptide-Leu721+Ser-peptide	P		His	Lys	Gln	Leu	Ser	Cys	Gln	Thr	Fodor & Vogt, 2002	16025
polyprotein	A4GTG2	1-1751	peptide-Arg1371+Val-peptide	P		Leu	Val	Gln	Arg	Val	Leu	Lys	Lys	Fodor & Vogt, 2002	16023
polyprotein (walleye epidermal hyperplasia virus type 1)	Q9WHI7		peptide-Asn+Val-peptide	P		Tyr	His	Gln	Asn	Val	Ile	Thr	Asp	Fodor & Vogt, 2002
polyprotein (walleye epidermal hyperplasia virus type 1)	Q9WHI7		peptide-Gly+Val-peptide	P		Met	Arg	Gln	Gly	Val	Leu	Lys	Glu	Fodor & Vogt, 2002
polyprotein (walleye epidermal hyperplasia virus type 2)	Q9WHJ2		peptide-Leu+Ser-peptide	P		Tyr	His	Gln	Leu	Ser	Leu	Arg	Tyr	Fodor & Vogt, 2002
polyprotein (walleye epidermal hyperplasia virus type 2)	Q9WHJ2		peptide-Gly+Val-peptide	P		Cys	Arg	Gln	Gly	Val	Leu	Arg	Glu	Fodor & Vogt, 2002
Val-Ser-Ala-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Ala	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Gln-Asn-Leu-Pro-Ile-Val-Gln			peptide-Leu5+Pro-peptide	N	AA	Ser	Gln	Asn	Leu	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Gln-Asn-Met-Pro-Ile-Val-Gln			peptide-Met5+Pro-peptide	N	AA	Ser	Gln	Asn	Met	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Gln-Asn-Phe-Pro-Ile-Val-Gln			peptide-Phe5+Pro-peptide	N	AA	Ser	Gln	Asn	Phe	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Gln	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Gln	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Gly-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Gly	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Leu-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Leu	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Lys-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Lys	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Phe-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Phe	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008
Val-Ser-Val-Asn-Tyr-Pro-Ile-Val-Gln			peptide-Tyr5+Pro-peptide	N	AA	Ser	Val	Asn	Tyr	Pro	Ile	Val	Gln	Eizert et al., 2008