Substrates for peptidase A02.020: porcine endogenous retrovirus peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
gag polyprotein Q8J4V6 1-1720 peptide-Leu194+Pro-peptide P Ile Ala Ile Leu Pro Leu Arg Thr Blusch et al., 2002 16009
gag polyprotein Q8J4V6 1-1720 peptide-Leu453+Ala-peptide P Thr Lys Ile Leu Ala Ala Val Val Blusch et al., 2002 16010
Glu-Ile-Ala-Ile-Leu-Pro-Leu-Arg-Thr Glu-Ile-Ala-Ile-Leu+Pro-Leu-Arg-Thr N Ile Ala Ile Leu Pro Leu Arg Thr Blusch et al., 2002
Glu-Ile-Ala-Thr-Leu-Pro-Leu-Arg-Thr Glu-Ile-Ala-Thr-Leu+Pro-Leu-Arg-Thr N Ile Ala Thr Leu Pro Leu Arg Thr Blusch et al., 2002
Leu-Thr-Lys-Ile-Leu-Ala-Ala-Val-Val Leu-Thr-Lys-Ile-Leu+Ala-Ala-Val-Val N Thr Lys Ile Leu Ala Ala Val Val Blusch et al., 2002
Thr-Leu-Gln-Leu-Pro-Ile-Thr-Val-Leu Thr-Leu-Gln-Leu+Pro-Ile-Thr-Val-Leu N Thr Leu Gln Leu Pro Ile Thr Val Blusch et al., 2002