Substrates for peptidase A01.076: Sapp2p peptidase (Candida parapsilosis)

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Dabcyl-Glu-His-Val-Lys-Leu-Val-Glu-EDANS			Dabcyl-Glu-His-Val-Lys+Leu-Val-Glu-EDANS	N	Glu	His	Val	Lys	Leu	Val	Glu	Ens	Merkerova et al., 2006
Dabcyl-Pro-Lys-Val-Glu-Leu-Thr-Gly-Glu-EDANS			Dabcyl-Pro-Lys-Val-Glu+Leu-Thr-Gly-Glu-EDANS	S	Pro	Lys	Val	Glu	Leu	Thr	Gly	Glu	Merkerova et al., 2006
Sapp2p peptidase ({Candida parapsilosis}) precursor	P32950	26-412	peptide-Asn53+Ala-peptide	P	Leu	Asp	Val	Asn	Ala	Thr	Ser	Glu	Merkerova et al., 2006
serum albumin	P02769	25-607	peptide-Lys65+Leu-peptide	N	Glu	His	Val	Lys	Leu	Val	Asn	Glu	Merkerova et al., 2006
serum albumin	P02769	25-607	peptide-Glu69+Leu-peptide	N	Leu	Val	Asn	Glu	Leu	Thr	Glu	Phe	Merkerova et al., 2006
serum albumin	P02769	25-607	peptide-Asp132+Ser-peptide	N	His	Lys	Asp	Asp	Ser	Pro	Asp	Leu	Merkerova et al., 2006
serum albumin	P02769	25-607	peptide-Glu206+Thr-peptide	N	Pro	Lys	Ile	Glu	Thr	Met	Arg	Glu	Merkerova et al., 2006