Structure for peptidase S54.016: GlpG peptidase (Escherichia-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

PDB	Organism	Resolution	Comment
2IC8	Escherichia coli	2.10 Å	mature
Catalytic residues are shown in ball-and-stick representation: Ser201 in orange and His254 in purple.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Escherichia coli
mature peptidase	2.10 Å	2IC8	2IC8	2IC8	2IC8	2IC8	2IC8	Wang et al., 2006
mature peptidase	2.30 Å	2IRV	2IRV	2IRV	2IRV	2IRV	2IRV	Ben-Shem et al., 2007
mature peptidase	0.00 Å	2LEP	2LEP	2LEP	2LEP	2LEP	2LEP	Sherratt et al., 2012
mature peptidase	2.60 Å	2NRF	2NRF	2NRF	2NRF	2NRF	2NRF	Wu et al., 2006
open-cap conformation	2.50 Å	2O7L	2O7L	2O7L	2O7L	2O7L	2O7L	Wang & Ha, 2007
mature peptidase	1.65 Å	2XOV	2XOV	2XOV	2XOV	2XOV	2XOV	Vinothkumar et al., 2010
complex with isocoumarin inhibitor	2.09 Å	2XOW	2XOW	2XOW	2XOW	2XOW	2XOW	Vinothkumar et al., 2010
mature peptidase	1.85 Å	2XTU	2XTU	2XTU	2XTU	2XTU	2XTU	Vinothkumar, 2011
mature peptidase	1.70 Å	2XTV	2XTV	2XTV	2XTV	2XTV	2XTV	Vinothkumar, 2011
mature peptidase	1.70 Å	3B44	3B44	3B44	3B44	3B44	3B44	Wang et al., 2007
mature peptidase	1.90 Å	3B45	3B45	3B45	3B45	3B45	3B45	Wang et al., 2007
mature peptidase	2.30 Å	3TXT	3TXT	3TXT	3TXT	3TXT	3TXT
mature peptidase	2.60 Å	3UBB	3UBB	3UBB	3UBB	3UBB	3UBB	Xue et al., 2012
mature peptidase	2.20 Å	3ZEB	3ZEB	3ZEB	3ZEB	3ZEB	3ZEB	Vosyka et al., 2013
mature peptidase	2.30 Å	3ZMH	3ZMH	3ZMH	3ZMH	3ZMH	3ZMH	Vinothkumar et al., 2013
mature peptidase	2.20 Å	3ZMI	3ZMI	3ZMI	3ZMI	3ZMI	3ZMI	Vinothkumar et al., 2013
mature peptidase	2.30 Å	3ZMJ	3ZMJ	3ZMJ	3ZMJ	3ZMJ	3ZMJ	Vinothkumar et al., 2013
mature peptidase	2.40 Å	3ZOT	3ZOT	3ZOT	3ZOT	3ZOT	3ZOT	Vinothkumar et al., 2013
mature peptidase	2.90 Å	4H1D	4H1D	4H1D	4H1D	4H1D	4H1D	Xue & Ha, 2013
mature peptidase	1.35 Å	4HDD	4HDD	4HDD	4HDD	4HDD	4HDD	Lazareno-Saez et al., 2013
mature peptidase	2.40 Å	4NJN	4NJN	4NJN	4NJN	4NJN	4NJN	Dickey et al., 2013
mature peptidase	2.40 Å	4NJP	4NJP	4NJP	4NJP	4NJP	4NJP	Dickey et al., 2013
complex with peptide derived inhibitor ac-rvrha-phenylethyl-ketoamide	2.16 Å	5MT6	5MT6	5MT6	5MT6	5MT6	5MT6
complex with peptide derived inhibitor ac-vrha-cmk	2.05 Å	5MT7	5MT7	5MT7	5MT7	5MT7	5MT7
complex with peptide derived inhibitor ac-rvrha-cmk	1.95 Å	5MT8	5MT8	5MT8	5MT8	5MT8	5MT8
a modular route to novel potent and selective inhibitors of rhomboid intramembrane proteases	1.79 Å	5MTF	5MTF	5MTF	5MTF	5MTF	5MTF