Structure for peptidase M12.001: astacin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

 

PDB Organism Resolution Comment
1AST Astacus astacus 1.80 Å mature
The catalytic zinc is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His141, His145 and His151 in purple. The catalytic residues are shown in ball-and-stick representation: Glu142 in blue and Tyr198 in green. Structurally important residues are shown in ball-and-stick representation: Gly148 in orange and Met196 in yellow.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Astacus astacus
mature  peptidase 1.80 Å 1AST 1AST 1AST 1AST 1AST 1AST Bode et al., 1992
zinc replaced with copper 1.90 Å 1IAA 1IAA 1IAA 1IAA 1IAA 1IAA Gomis-Ruth et al., 1994
zinc replaced with cobalt 1.79 Å 1IAB 1IAB 1IAB 1IAB 1IAB 1IAB Gomis-Ruth et al., 1994
zinc replaced with mercury 2.10 Å 1IAC 1IAC 1IAC 1IAC 1IAC 1IAC Gomis-Ruth et al., 1993
zinc removed 2.30 Å 1IAD 1IAD 1IAD 1IAD 1IAD 1IAD Gomis-Ruth et al., 1993
zinc replaced with nickel 1.83 Å 1IAE 1IAE 1IAE 1IAE 1IAE 1IAE Gomis-Ruth et al., 1994
mature  peptidase 2.14 Å 1QJI 1QJI 1QJI 1QJI 1QJI 1QJI Grams et al., 1996
complex with Pro-Leu-Gly-hydroxamic acid inhibitor 1.86 Å 1QJJ 1QJJ 1QJJ 1QJJ 1QJJ 1QJJ Grams et al., 1996
precursor 0.00 Å 3LQ0 3LQ0 3LQ0 3LQ0 3LQ0 3LQ0 Guevara et al., 2010
complex mouse fetuin-b 3.10 Å 6HT9 6HT9 6HT9 6HT9 6HT9 6HT9