Structure for peptidase A01.012: rhizopuspepsin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
6APR Rhizopus microsporus 2.50 Å complex with pepstatin
Active site residues are shown in ball-and-stick representation: Asp103 and Asp286 in pink, Tyr145 in green. Pepstatin is shown in grey in ball-and-stick representation.
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TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Rhizopus microsporus
pH 4.6 2.10 Å 1UH7 1UH7 1UH7 1UH7 1UH7 1UH7 Prasad & Suguna, 2003
pH 8.0 2.30 Å 1UH8 1UH8 1UH8 1UH8 1UH8 1UH8 Prasad & Suguna, 2003
pH 7.0 2.00 Å 1UH9 1UH9 1UH9 1UH9 1UH9 1UH9 Prasad & Suguna, 2003
mature  peptidase 1.80 Å 2APR 2APR 2APR 2APR 2APR 2APR Suguna et al., 1987
complex with psi-(CH2-NH)-D-His-Pro-Phe-His-Phe-Phe-Val-Tyr 1.80 Å 3APR 3APR 3APR 3APR 3APR 3APR Suguna et al., 1987
complex with a pepstatin-like renin inhibitor 2.50 Å 4APR 4APR 4APR 4APR 4APR 4APR Suguna et al., 1992
complex with a pepstatin-like renin inhibitor 2.10 Å 5APR 5APR 5APR 5APR 5APR 5APR Suguna et al., 1992
complex with pepstatin 2.50 Å 6APR 6APR 6APR 6APR 6APR 6APR Suguna et al., 1992