Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q99616

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
16	unknown peptidase	1-98	P	release of a signal peptide	NT	Uguccioni et al., 1996
21	unknown peptidase	1-98	P		NT	<%Agarwal et al., 2012[]%>
23	unknown peptidase	1-98	P		NT	<%Agarwal et al., 2012[]%>
26	matrix metallopeptidase-1	17-98	P			McQuibban et al., 2002
26	matrix metallopeptidase-3	17-98	P	normal turnover		McQuibban et al., 2002
27	matrix metallopeptidase-1	17-98	P	normal turnover		McQuibban et al., 2002
27	matrix metallopeptidase-3	17-98	P	normal turnover		McQuibban et al., 2002
30	matrix metallopeptidase-1	17-98	P	normal turnover		McQuibban et al., 2002