Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q8NBP7

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
30	unknown peptidase	1-692	P		NT	<%Agarwal et al., 2012[]%>
48	meprin beta subunit	31-692	N		MS	Becker-Pauly et al., 2011
49	meprin beta subunit	31-692	N		MS	Becker-Pauly et al., 2011
53	meprin beta subunit	31-692	N		MS	Becker-Pauly et al., 2011
82	PCSK9 peptidase	31-692	P			Seidah et al., 2003
152	PCSK9 peptidase	31-692	P			Benjannet et al., 2004
218	furin	31-692	P			Mayer et al., 2008
218	PCSK5 peptidase	153-692	P			Benjannet et al., 2006
418	meprin beta subunit	153-692	N		MS	Becker-Pauly et al., 2011
443	meprin alpha subunit	153-692	N		MS	Becker-Pauly et al., 2011