Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q62465

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-406	P		NT	<%Agarwal et al., 2012[]%>
50	matrix metallopeptidase-2	2-406	N		MS	Prudova et al., 2010
52	matrix metallopeptidase-2	2-406	N		MS	Prudova et al., 2010
63	cathepsin E	2-406	P		MS	Impens et al., 2010
64	cathepsin E	2-406	P		MS	Impens et al., 2010
66	cathepsin D	2-406	P		MS	Impens et al., 2010
66	cathepsin E	2-406	P		MS	Impens et al., 2010
68	cathepsin D	2-406	P		MS	Impens et al., 2010
120	matrix metallopeptidase-2	2-406	N		MS	auf dem Keller et al., 2010
129	matrix metallopeptidase-2	2-406	N		MS	auf dem Keller et al., 2010
350	cathepsin E	2-406	P		MS	Impens et al., 2010