Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q61233

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-627	P		NT	<%Agarwal et al., 2012[]%>
37	cathepsin D	2-627	P		MS	Impens et al., 2010
129	cathepsin D	2-627	P		MS	Impens et al., 2010
163	cathepsin D	2-627	P		MS	Impens et al., 2010
348	cathepsin E	2-627	P		MS	Impens et al., 2010
349	cathepsin E	2-627	P		MS	Impens et al., 2010
462	cathepsin E	2-627	P		MS	Impens et al., 2010
475	cathepsin E	2-627	P		MS	Impens et al., 2010
477	cathepsin D	2-627	P		MS	Impens et al., 2010
477	cathepsin E	2-627	P		MS	Impens et al., 2010
568	cathepsin D	2-627	P		MS	Impens et al., 2010
568	cathepsin E	2-627	P		MS	Impens et al., 2010
574	cathepsin D	2-627	P		MS	Impens et al., 2010
613	cathepsin E	2-627	P		MS	Impens et al., 2010
616	cathepsin D	2-627	P		MS	Impens et al., 2010
616	cathepsin E	2-627	P		MS	Impens et al., 2010
617	cathepsin E	2-627	P		MS	Impens et al., 2010