Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q16643

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-649	P		NT	<%Agarwal et al., 2012[]%>
89	caspase-6	2-649	P		MS	Klaiman et al., 2008
125	caspase-6	2-649	P		MS	Klaiman et al., 2008
167	caspase-3	2-649	P		MS	Impens et al., 2010
279	astacin	276-291	N		MS	Becker-Pauly et al., 2011
280	astacin	277-291	N		MS	Becker-Pauly et al., 2011
629	caspase-6	2-649	P		MS	Klaiman et al., 2008