Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q15843

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
10	peptidyl-Lys metallopeptidase	1-81	N		MS
11	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
16	meprin beta subunit	13-25	N		MS	Becker-Pauly et al., 2011
21	peptidyl-Lys metallopeptidase	1-81	N		MS
25	trypsin 1	1-76	N		MS	Schilling & Overall, 2008
40	matrix metallopeptidase-2	34-53	N		MS	Schilling & Overall, 2008
53	glutamyl endopeptidase I	1-76	N		MS	Schilling & Overall, 2008
76	SENP8 peptidase	1-81	P			Mendoza et al., 2003