Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q02750

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-393	P		NT	<%Agarwal et al., 2012[]%>
8	anthrax lethal factor	2-393	N			Vitale et al., 2000
16	unknown peptidase	2-393	P		MS	Mahrus et al., 2008
21	meprin beta subunit	2-393	N		MS	Becker-Pauly et al., 2011
25	meprin beta subunit	2-393	N		MS	Becker-Pauly et al., 2011
277	matrix metallopeptidase-2	269-291	N		MS	Schilling & Overall, 2008
282	unknown peptidase	2-393	P		MS	Mahrus et al., 2008
291	trypsin 1	2-393	N		MS	Schilling & Overall, 2008
380	cathepsin B	364-389	N		MS	Biniossek et al., 2011