Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q01853

,

Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-806	P		NT	<%Agarwal et al., 2012[]%>
25	matrix metallopeptidase-2	2-806	N		MS	Kleifeld et al., 2010
30	cathepsin E	2-806	P		MS	Impens et al., 2010
40	matrix metallopeptidase-2	2-806	N		MS	auf dem Keller et al., 2010
69	cathepsin E	2-806	P		MS	Impens et al., 2010
98	matrix metallopeptidase-2	2-806	N		MS	auf dem Keller et al., 2010
174	matrix metallopeptidase-2	2-806	N		MS	auf dem Keller et al., 2010
198	cathepsin E	2-806	P		MS	Impens et al., 2010
240	matrix metallopeptidase-9	2-806	N		MS	Prudova et al., 2010
277	matrix metallopeptidase-2	2-806	N		MS	auf dem Keller et al., 2010
328	cathepsin E	2-806	P		MS	Impens et al., 2010
463	matrix metallopeptidase-2	2-806	N		MS	Kleifeld et al., 2010
572	matrix metallopeptidase-2	2-806	N		MS	auf dem Keller et al., 2010
638	matrix metallopeptidase-2	2-806	N		MS	auf dem Keller et al., 2010
674	cathepsin E	2-806	P		MS	Impens et al., 2010
719	matrix metallopeptidase-2	2-806	N		MS	auf dem Keller et al., 2010
757	cathepsin E	2-806	P		MS	Impens et al., 2010
758	cathepsin E	2-806	P		MS	Impens et al., 2010