Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P78556

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
26	unknown peptidase	1-96	P		NT	<%Agarwal et al., 2012[]%>
27	unknown peptidase	1-96	P		NT	<%Agarwal et al., 2012[]%>
45	cathepsin D	27-96	P	normal turnover		Hasan etal, 2006
48	cathepsin D	27-96	P	normal turnover		Hasan etal, 2006
78	cathepsin D	27-96	P	normal turnover		Hasan etal, 2006
81	cathepsin D	27-96	P	normal turnover		Hasan etal, 2006
84	cathepsin D	27-96	P	normal turnover		Hasan etal, 2006
90	unknown peptidase	1-96	P		NT	<%Agarwal et al., 2012[]%>
92	cathepsin B	27-96	P	normal turnover		Hasan etal, 2006
93	unknown peptidase	1-96	P		NT	<%Agarwal et al., 2012[]%>