Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P63101

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
5	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010
6	cathepsin E	1-245	P		MS	Impens et al., 2010
22	cathepsin D	1-245	P		MS	Impens et al., 2010
22	cathepsin E	1-245	P		MS	Impens et al., 2010
23	cathepsin D	1-245	P		MS	Impens et al., 2010
23	cathepsin E	1-245	P		MS	Impens et al., 2010
24	cathepsin D	1-245	P		MS	Impens et al., 2010
24	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010
25	cathepsin E	1-245	P		MS	Impens et al., 2010
25	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010
26	cathepsin D	1-245	P		MS	Impens et al., 2010
26	cathepsin E	1-245	P		MS	Impens et al., 2010
27	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010
28	cathepsin E	1-245	P		MS	Impens et al., 2010
42	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010
43	cathepsin E	1-245	P		MS	Impens et al., 2010
44	cathepsin D	1-245	P		MS	Impens et al., 2010
44	cathepsin E	1-245	P		MS	Impens et al., 2010
66	cathepsin E	1-245	P		MS	Impens et al., 2010
117	cathepsin D	1-245	P		MS	Impens et al., 2010
117	cathepsin E	1-245	P		MS	Impens et al., 2010
154	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010
157	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010
158	matrix metallopeptidase-2	1-245	N		MS	auf dem Keller et al., 2010