Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P60866

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-119	P		NT	<%Agarwal et al., 2012[]%>
4	granzyme A	1-119	N			Van Damme et al., 2010
5	unknown peptidase	1-119	P		MS	Van Damme et al., 2005
8	meprin alpha subunit	5-19	N		MS	Becker-Pauly et al., 2011
8	meprin beta subunit	5-19	N		MS	Becker-Pauly et al., 2011
8	trypsin 1	2-119	N		MS	Schilling & Overall, 2008
19	trypsin 1	2-119	N		MS	Schilling & Overall, 2008
33	peptidyl-Lys metallopeptidase	1-119	N		MS
38	granzyme B (Homo sapiens-type)	2-119	N		MS	Van Damme et al., 2010
43	peptidyl-Lys metallopeptidase	1-119	N		MS
87	trypsin 1	2-119	N		MS	Schilling & Overall, 2008
99	trypsin 1	2-119	N		MS	Schilling & Overall, 2008