Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P59998

,

Click here to display alignment and conservation of cleavage sites of this sequence with close homologues. This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-168	P		NT	<%Agarwal et al., 2012[]%>
44	trypsin 1	2-168	N		MS	Schilling & Overall, 2008
55	trypsin 1	2-168	N		MS	Schilling & Overall, 2008
97	trypsin 1	2-168	N		MS	Schilling & Overall, 2008
105	trypsin 1	2-168	N		MS	Schilling & Overall, 2008
158	trypsin 1	2-168	N		MS	Schilling & Overall, 2008
166	trypsin 1	2-168	N		MS	Schilling & Overall, 2008
167	carboxypeptidase A4	2-168	N		MS	Van Damme et al., 2010